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SAGE / SAGE1 belongs to a class of genes that are activated in tumors. These genes are expressed in tumors of different histologic types but not in normal tissues, except for spermatogenic cells and, for some, placenta. The proteins encoded by these genes appear to be strictly tumor specific, and hence may be excellent sources of antigens for cancer immunotherapy. This gene is expressed in sarcomas.
Gene Name: | Sarcoma Antigen 1 |
Synonyms: | SAGE1, Cancer/testis antigen 14, Sarcoma antigen 1, Putative tumor antigen, CT14, SAGE |
Target Sequences: | NM_018666 NP_061136.2 Q9NXZ1 |
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