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SAE1

SUMO1 activating enzyme subunit 1

The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Gene Name: SUMO1 activating enzyme subunit 1
Synonyms: SAE1, Activator of SUMO1, AOS1, UBLE1A, HSPC140, SUA1
Target Sequences: NM_005500 NP_005491.1 Q9UBE0

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Products
Antibodies (53)
Primary (53)
SAE1 (53)
Human (53)
Mouse (24)
Rat (17)
Bat (1)
Bovine (10)
Chimpanzee (6)
Dog (10)
Guinea pig (3)
Horse (4)
Monkey (8)
Orangutan (6)
Pig (6)
Rabbit (7)
Xenopus (3)
Zebrafish (3)
IHC (24)
IHC-P (10)
WB (49)
DB (1)
ELISA (22)
ICC (4)
IF (11)
IP (2)
Peptide-ELISA (3)
rabbit (36)
mouse (16)
goat (1)
Product Group
IHCPlus (3)
IgG (22)
IgG1 (8)
IgG1,l (1)
IgG2b (6)
monoclonal mc (16)
polyclonal pc (37)
1G4-1G5 (1)
1G8 (2)
2946C4a (1)
OTI2B2 (2)
OTI3C11 (2)
OTI3C3 (2)
OTI6B11 (2)
OTI6C7 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
Carrier-free (6)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (42)
aa300-329 (7)
N-Terminus (4)
aa71-120 (4)
pSer185 (2)
190-270 aa, Internal (1)
Internal (1)
aa221-270 (1)
aa296-346 (1)
aa3-247 (1)
aa334-346 (1)
No (53)
SAE1 Antibody - Anti-SAE1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.
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SAE1 Mouse anti-Human Monoclonal (1G4-1G5) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
SAE1 Antibody - Anti-SAE1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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SAE1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$535
SAE1 Antibody - Immunohistochemical analysis of SAE1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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SAE1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
SAE1 Antibody - IHC of paraffin-embedded A549 Xenograft using SAE1 antibody at 1:100 dilution.
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SAE1 Rabbit anti-Human Polyclonal (aa3-247) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
SAE1 Antibody - Anti-SAE1 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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SAE1 Mouse anti-Human Monoclonal (Carrier-free) (1G8) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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SAE1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
SAE1 Antibody - Western blot of SAE1 antibody
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SAE1 Rabbit anti-Human Polyclonal (190-270 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SAE1 Antibody - IHC of paraffin-embedded Human pancreas tissue using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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SAE1 Mouse anti-Human Monoclonal (OTI3C3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
SAE1 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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SAE1 Mouse anti-Human Monoclonal (Carrier-free) (OTI3C3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SAE1 Antibody - IHC of paraffin-embedded Human pancreas tissue using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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SAE1 Mouse anti-Human Monoclonal (OTI6C7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
SAE1 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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SAE1 Mouse anti-Human Monoclonal (Carrier-free) (OTI6C7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SAE1 Antibody - IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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SAE1 Mouse anti-Human Monoclonal (OTI6B11) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
SAE1 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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SAE1 Mouse anti-Human Monoclonal (Carrier-free) (OTI6B11) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SAE1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using SAE1 Polyclonal Antibody at dilution of 1:15.
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SAE1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SAE1 Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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SAE1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SAE1 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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SAE1 Rabbit anti-Human Polyclonal (aa300-329) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
SAE1 Antibody - Western blot of 293 cell lysate using AOS1 Antibody
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SAE1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
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SAE1 Rabbit anti-Human Polyclonal (aa300-329) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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SAE1 Rabbit anti-Human Polyclonal (aa300-329) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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SAE1 Rabbit anti-Human Polyclonal (aa300-329) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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SAE1 Rabbit anti-Human Polyclonal (aa300-329) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
SAE1 Antibody - Peptide - + Immunofluorescence analysis of HuvEc cells, using AOS1 antibody.
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SAE1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
SAE1 Antibody - Western blot of immunized recombinant protein using SAE1 antibody.
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SAE1 Mouse anti-Human Monoclonal (2946C4a) Antibody
Human
DB, ICC, WB
Unconjugated
50 µg/$474
SAE1 Antibody - Immunofluorescence analysis of HUVEC cells, using AOS1 Antibody. The picture on the right is blocked with the synthesized peptide.
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SAE1 Rabbit anti-Human Polyclonal (aa221-270) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SAE1 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
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SAE1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Viewing 26-50 of 53 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).