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S100B / S100 Beta

S100 calcium binding protein B

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Gene Name: S100 calcium binding protein B
Synonyms: S100B, NEF, Protein S100-B, S100, S100 calcium binding protein B, S100 calcium-binding protein B, S100beta, S-100 protein beta chain, S-100 protein subunit beta, S100-B
Target Sequences: NM_006272 NP_006263.1 P04271

Publications (3)

1
Striatal astrocytes engulf dopaminergic debris in Parkinson's disease: A study in an animal model. Morales I, Sanchez A, Rodriguez-Sabate C, Rodriguez M,. PloS one. 2017 12:e0185989. (WB; Human) [Full Text Article] [PubMed:29028815]
2
The astrocytic response to the dopaminergic denervation of the striatum. Morales I, Sanchez A, Rodriguez-Sabate C, Rodriguez M. Journal of neurochemistry. 2016 October;139:81-95. [Full Text Article] [PubMed:27230040]
3
Neuroglial transmitophagy and Parkinson's disease. Ingrid Morales, Alberto Sanchez, Ricardo Puertas-Avendaño, Clara Rodriguez-Sabate, Adrian Perez-Barreto, Manuel Rodriguez. Glia. 2020 November;68:2277-2299. [Full Text Article] [PubMed:32415886]

☰ Filters
Products
ELISA Kits (33)
Competitive EIA (2)
Custom (2)
Development Kit (4)
Sandwich (21)
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S100B / S100 Beta (33)
Human (10)
Mouse (7)
Rat (6)
Chicken (1)
Guinea pig (1)
Pig (2)
Rabbit (5)
Product Group
DevKit DuoPlus (4)
12 x 8-Well Microstrips (2)
96-Well Microplate (5)
96-Well Strip Plate (22)
Antibody Pair and Standard (4)
No (33)
Cell Culture Supernatants (10)
Cell Lysates (9)
Cerebrospinal Fluid (1)
Plasma (30)
Serum (30)
Tissue Homogenates (16)
S100B / S100 Beta ELISA Kit
Select
Sandwich
96-Well Microplate
Pig
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$745
S100B / S100 Beta ELISA Kit
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Sandwich
96-Well Microplate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
S100B / S100 Beta ELISA Kit
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Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
S100B / S100 Beta ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
S100B / S100 Beta ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$764
S100B / S100 Beta ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
3.12 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
S100B / S100 Beta ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
S100B / S100 Beta ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
S100B / S100 Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
S100B / S100 Beta ELISA Kit
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Sandwich
96-Well Microplate
Mouse
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
S100B / S100 Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
S100B / S100 Beta ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
S100B / S100 Beta ELISA Kit
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Sandwich
96-Well Microplate
Rabbit
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
S100B / S100 Beta ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
S100B / S100 Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
S100B / S100 Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
S100B / S100 Beta ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,182; 1000 Wells/$1,747
S100B / S100 Beta ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
S100B / S100 Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
S100B / S100 Beta ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
S100B / S100 Beta ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
S100B / S100 Beta ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
S100B / S100 Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
S100B / S100 Beta ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
27.43 - 20000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$968
S100B / S100 Beta ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).