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RYR2 / Ryanodine Receptor 2
ryanodine receptor 2 (cardiac)
Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.
| Gene Name: | ryanodine receptor 2 (cardiac) |
| Family/Subfamily: | Ion Channel , Ryanodine receptor |
| Synonyms: | RYR2, ARVD2, ARVC2, Cardiac ryanodine receptor, Cardiac-type ryaodine receptor, HRYR-2, RYR-2, VTSIP, Islet-type ryanodine receptor, Kidney-type ryanodine receptor, Ryanodine receptor, Ryanodine receptor 2, Ryanodine receptor 2 (cardiac), RyR, Type 2 ryanodine receptor |
| Target Sequences: | NM_001035 NP_001026.2 Q92736 |
Publications (2)
1
Xanthine Oxidase Inhibitor Allopurinol Prevents Oxidative Stress-Mediated Atrial Remodeling in Alloxan-Induced Diabetes Mellitus Rabbits. Yang Y, Zhao J, Qiu J, Li J, Liang X, Zhang Z, Zhang X, Fu H, Korantzopoulos P, Letsas KP, Tse G, Li G, Liu T. Journal of the American Heart Association. 2018 May;7:pii: e008807. (Dog)
[Full Text Article]
[PubMed:29720500]
[PMC:PMC6015332]
Related Antibodies: LS-C93425.
2
Cardiac Protection of Valsartan on Juvenile Rats with Heart Failure by Inhibiting Activity of CaMKII via Attenuating Phosphorylation. Wu Y, Si F, Ji X, Jiang K, Song S, Yi Q. BioMed research international. 2017 2017:4150158. (ICC; Human)
[Full Text Article]
[PubMed:28536695]
[PMC:PMC5425837]
Related Antibodies: LS-C358303.
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RYR2 / Ryanodine Receptor 2
(19)
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(18)
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(10)
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(18)
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(15)
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(18)
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(1)
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(1)
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(1)
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(16)
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(3)
2750-2830 aa
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pSer2815
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Publications
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(17)
Yes
(2)
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (pSer2808) Antibody
Rabbit, Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$315
RYR2 / Ryanodine Receptor 2 Mouse anti-Dog Monoclonal Antibody
Amphibian, Fish, Dog, Rat
IHC, IHC-P, IP, WB
Unconjugated
100 µg/$1,031
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Mouse, Rat, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (2750-2830 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (pSer2808) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (Asn2802) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (pSer2830) Antibody
Human
WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (Ab-2808) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (2750-2830 aa) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (pSer2808) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
100 µg/$357
RYR2 / Ryanodine Receptor 2 Rabbit anti-Human Polyclonal (pSer2815) Antibody
Human
WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
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