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RUNX3

runt-related transcription factor 3

RUNX3 is a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: runt-related transcription factor 3
Synonyms: RUNX3, Acute myeloid leukemia gene 2, CBF-alpha-3, PEA2 alpha C, PEBP2 alpha C, PEBP2-alpha C, PEBP2A3, PEBP2aC, AML2, Oncogene AML-2, CBFA3, PEA2-alpha C, Transcription factor AML2
Target Sequences: NM_004350 NP_004341.1 Q13761

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ELISA Kits (2)
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Cell Lysates (2)
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RUNX3 ELISA Kit
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DNA Binding
12 x 8-Well Microstrips
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$694
RUNX3 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).