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RUFY1

RUN and FYVE domain containing 1

RUFY1 is a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name:	RUN and FYVE domain containing 1
Synonyms:	RUFY1, FYVE-finger protein EIP1, RABIP4, La-binding protein 1, Rab4-interacting protein, ZFYVE12
Target Sequences:	NM_025158 NP_079434.3 Q96T51

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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