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RTN3 / Reticulon 3

reticulon 3

RTN3 / Reticulon 3 belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.

Gene Name: reticulon 3
Family/Subfamily: Reticulon
Synonyms: RTN3, ASYIP, ASY interacting protein, HAP, NSP-like protein II, NSPL2, RTN3-A1, NSP-like protein 2, Reticulon-3, Homolog of ASY protein, NSPLII, Reticulon 3
Target Sequences: NM_006054 NP_006045.1 O95197

☰ Filters
Antibodies (14)
Proteins (4)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (14)
Recombinant (2)
Sandwich (1)
RTN3 / Reticulon 3 (19)
Human (15)
Mouse (2)
Rat (2)
IHC (10)
IHC-P (5)
WB (8)
ELISA (6)
ICC (1)
IF (3)
IP (3)
rabbit (8)
mouse (6)
Product Group
IHCPlus (4)
IgG (5)
IgG2a (6)
monoclonal mc (6)
polyclonal pc (8)
10A8 (2)
1E+11 (2)
96-Well Strip Plate (1)
Unconjugated (14)
N-Terminus (1)
aa1017-1032 (1)
aa550-600 (1)
aa750-800 (1)
No (19)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
Select
RTN3 / Reticulon 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
RTN3 / Reticulon 3 Antibody - RTN3 / Reticulon 3 antibody. IHC(P): Rat Brain Tissue.
Select
RTN3 / Reticulon 3 Rabbit anti-Human Polyclonal (aa1017-1032) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$431
RTN3 / Reticulon 3 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
Select
RTN3 / Reticulon 3 Rabbit anti-Human Polyclonal (aa550-600) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
RTN3 / Reticulon 3 Antibody - Human Brain, Cerebellum, White Matter: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:50.
Select
RTN3 / Reticulon 3 Mouse anti-Human Monoclonal (1E+11) Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µl/$460
RTN3 / Reticulon 3 Protein - 12.5% SDS-PAGE of human RTN3 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
51.7 kDa
2 µg/$439
RTN3 / Reticulon 3 Antibody - Anti-RTN3 / Reticulon 3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Select
RTN3 / Reticulon 3 Mouse anti-Human Monoclonal (10A8) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$460
RTN3 / Reticulon 3 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
Select
RTN3 / Reticulon 3 Rabbit anti-Human Polyclonal (aa750-800) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
Select
RTN3 / Reticulon 3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
RTN3 / Reticulon 3 Antibody - RTN3 Antibody in Immunofluorescence (IF)
Select
RTN3 / Reticulon 3 Mouse anti-Human Monoclonal (1E+11) Antibody
Human
ICC, IF
Unconjugated
100 µl/$518
RTN3 / Reticulon 3 Antibody - Confocal Immunofluorescence (IF) analysis of HeLa (A), A431 (B) and THP-1 (C) cells using Rtn-3 Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye.
Select
RTN3 / Reticulon 3 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
RTN3 / Reticulon 3 Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded human lung cancer (left) and breast cancer (right) with DAB staining using Rtn-3 Monoclonal Antibody.
Select
RTN3 / Reticulon 3 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
Select
RTN3 / Reticulon 3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
RTN3 / Reticulon 3 Antibody - RTN3 Antibody in Immunohistochemistry (IHC)
Select
RTN3 / Reticulon 3 Mouse anti-Human Monoclonal (10A8) Antibody
Human
IHC
Unconjugated
100 µl/$518
RTN3 / Reticulon 3 Antibody - Western blot analysis of extracts of HeLa cells, using RTN3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
RTN3 / Reticulon 3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RTN3 / Reticulon 3 Antibody - Western blot analysis of extracts of HeLa cells using RTN3 Polyclonal Antibody at dilution of 1:1000.
Select
RTN3 / Reticulon 3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
RTN3 / Reticulon 3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RTN3 / Reticulon 3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
RTN3 / Reticulon 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.4 kDa
20 µg/$150
RTN3 / Reticulon 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.4 kDa
100 µg/$494
Viewing 1-19 of 19 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).