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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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RSPO4

R-spondin 4

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway.

Gene Name: R-spondin 4
Synonyms: RSPO4, C20orf182, CRISTIN4, DJ824F16.3, HRspo4, R-spondin 4, R-spondin-4, Roof plate-specific spondin-4, R-spondin family, member 4
Target Sequences: Q2I0M5 Q2I0M5

Filtered by: None
Target
RSPO4 (9)
Reactivity
Human (8)
Mouse (1)
Application
IHC (8)
IHC-P (1)
WB (9)
Flo (8)
ELISA (8)
Host
rabbit (8)
rat (1)
Isotype
IgG (7)
IgG2b (1)
Clonality
monoclonal mc (1)
polyclonal pc (8)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (3)
Epitope
aa199-228 (8)
aa21-197 (1)
Publications
No (9)
Showing 1-9 of 9 results

RSPO4 Antibody (aa21-197) LS-C75550
Rat Monoclonal (IgG2b) to Mouse RSPO4
Mouse
ELISA, WB
Unconjugated
100µg  $650.00

RSPO4 Antibody (aa199-228) LS-C162784
Rabbit Polyclonal to Human RSPO4
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
RSPO4 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
RSPO4 Antibody western blot of Jurkat cell line lysates (15 ug/lane). The RSPO4 antibody detected the RSPO4 protein (arrow).

RSPO4 Antibody (aa199-228) LS-C324849
Rabbit Polyclonal (IgG) to Human RSPO4
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl  $590.00

RSPO4 Antibody (aa199-228, Biotin) LS-C240281
Rabbit Polyclonal (IgG) to Human RSPO4
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl  $740.00

RSPO4 Antibody (aa199-228, FITC) LS-C240283
Rabbit Polyclonal (IgG) to Human RSPO4
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl  $740.00

RSPO4 Antibody (aa199-228, AP) LS-C240279
Rabbit Polyclonal (IgG) to Human RSPO4
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl  $740.00

RSPO4 Antibody (aa199-228, APC) LS-C240280
Rabbit Polyclonal (IgG) to Human RSPO4
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl  $740.00

RSPO4 Antibody (aa199-228, Azide-free, HRP) LS-C248057
Rabbit Polyclonal (IgG) to Human RSPO4
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

RSPO4 Antibody (aa199-228, PE) LS-C240284
Rabbit Polyclonal (IgG) to Human RSPO4
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl  $740.00
Showing 1-9 of 9 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).