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Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain.
Gene Name: | remodeling and spacing factor 1 |
Synonyms: | RSF1, HBV pX associated protein-8, HBXAP, RSF-1, XAP8, HBV pX-associated protein 8, p325 |
Target Sequences: | NM_016578 NP_057662.3 Q96T23 |
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