RRM2B / P53R2

ribonucleotide reductase M2 B (TP53 inducible)

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and g-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumor suppression.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

RRM2B / P53R2 (8)

Publications

No (8)

Tag

GST, N-terminus (2)

His (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (2)

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RRM2B / P53R2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129791

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.2 kDa

Price:

100 µg/$494

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Human RRM2B / P53R2 Protein (Recombinant GST, N-terminus) (aa3-84) - LS-G62360

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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RRM2B / P53R2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113072

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.6 kDa

Price:

100 µg/$494

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Human RRM2B / P53R2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69679

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.6 kDa

Price:

20 µg/$1,107

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Human RRM2B / P53R2 Protein (Recombinant GST, N-terminus) (aa1-351) - LS-G56786

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human RRM2B / P53R2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85250

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.2 kDa

Price:

20 µg/$150

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Human RRM2B / P53R2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85252

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.6 kDa

Price:

20 µg/$150

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Human RRM2B / P53R2 Protein (Recombinant His) (Met1-Phe351) - LS-G97838

Source:

E. coli

Tag:

His

Molecular Weight:

42.6 kDa

Price:

100 µg/$970

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