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RRAGB / RAGB
Ras-related GTP binding B
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.
| Gene Name: | Ras-related GTP binding B |
| Synonyms: | RRAGB, BA465E19.1, RAGB, Ras-related GTP binding B, GTP-binding protein ragB, Rag B |
| Target Sequences: | NM_016656 NP_057740.2 Q5VZM2 |
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