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RRAGA

Ras-related GTP binding A

Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

Gene Name: Ras-related GTP binding A
Synonyms: RRAGA, FIP-1, FIP1, RAGA, Ras-related GTP binding A, Rag A
Target Sequences: NM_006570 NP_006561.1 Q7L523

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
RRAGA (5)
No (5)
GST (2)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
RRAGA Protein - Purified recombinant protein RRAGA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
36.4 kDa
20 µg/$1,107
RRAGA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
36.4 kDa
20 µg/$150
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E. coli
GST
56.4 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RRAGA Protein - 12.5% SDS-PAGE of human RRAGA stained with Coomassie Blue
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Wheat Germ Extract
GST
60.17 kDa
10 µg/$479; 25 µg/$670
RRAGA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
36.4 kDa
100 µg/$494
Viewing 1-5 of 5 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).