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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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RPRD1A
Regulation of nuclear pre-mRNA domain containing 1A
RPRD1A is a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G(1)/S phase progression. This protein also forms homo- and hetrodimers with the protein, regulation of nuclear pre-mRNA domain-containing protein 1B, to form a scaffold that interacts with the C-terminal domain of RNA polymerase II subunit B1 and regulates several aspects of transcription. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 16.
| Gene Name: | Regulation of nuclear pre-mRNA domain containing 1A |
| Synonyms: | RPRD1A, HsT3101, p15INK4B-related protein, p15RS |
| Target Sequences: | AF419845 AAL15972.1 Q96P16 |
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