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RPLP2

ribosomal protein, large, P2

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Gene Name: ribosomal protein, large, P2
Synonyms: RPLP2, D11S2243E, LP2, Ribosomal protein, large, P2, RPP2, p2, Ribosomal protein p2, acidic
Target Sequences: NM_001004 NP_000995.1 P05387

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Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
RPLP2 (7)
No (7)
6His, N-terminus (1)
GST (2)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (2)
Human (6)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
RPLP2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RPLP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
11.5 kDa
20 µg/$150
RPLP2 Protein
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E. coli
GST
38.8 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RPLP2 Protein - 12.5% SDS-PAGE of human RPLP2 stained with Coomassie Blue
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Wheat Germ Extract
GST
38.39 kDa
2 µg/$439
RPLP2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
15.7 kDa
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RPLP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
11.5 kDa
100 µg/$494
RPLP2 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).