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RPA4
replication protein A4, 30kDa
As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
| Gene Name: | replication protein A4, 30kDa |
| Synonyms: | RPA4, HSU24186, Replication protein A4, 30kDa, RF-A protein 4, RP-A p30, Replication protein A4, 34kDa, Replication factor A protein 4 |
| Target Sequences: | NM_013347 NP_037479.1 Q13156 |
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