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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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RP9
retinitis pigmentosa 9 (autosomal dominant)
RP9 can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene.
| Gene Name: | retinitis pigmentosa 9 (autosomal dominant) |
| Synonyms: | RP9, PAP-1, Pim-1-associated protein, Retinitis pigmentosa 9 protein |
| Target Sequences: | AA526926 |
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