RNGTT / HCAP

RNA guanylyltransferase and 5'-phosphatase

RNGTT is a non-receptor like tyrosine phosphatase. Mammalian capping enzymes are bifunctional proteins with both RNA 5 '- triphosphatase and guanylyltransferase activities. The N-terminal 237- aa triphosphatase domain contains (I/V)HCXXGXXR(S/T)G, a sequence corresponding to the conserved active-site motif in protein tyrosine phosphatases (PTPs). mRNA capping requires the sequential action of three enzymatic activities: RNA triphosphatase, guanylyl-transferase, and methyltransferase. The m7GpppN cap of eukaryotic mRNA is formed by a series of three enzymatic reactions in which the 5'-triphosphate end of nascent pre-mRNA is hydrolyzed to a 5'-diphosphate by RNA triphosphatase, then capped with GMP by GTP: RNA guanylyltransferase, and methylated by RNA (guanine-N7) methyltransferase. The human mRNA capping enzyme has two alternatively spliced isoforms of 597 and 541 aa that differ in their C-terminus.

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Products

Antibodies (13)

Proteins (5)

ELISA Kits (2)

Type

Custom (2)

Over-Expression Lysate (2)

Primary (13)

Recombinant (3)

Target

RNGTT / HCAP (20)

Reactivity

Human (13)

Mouse (10)

Rat (6)

Bat (3)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Horse (3)

Monkey (3)

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Application

IHC (6)

IHC-P (4)

WB (13)

ELISA (2)

ICC (1)

IF (3)

IP (2)

Host

rabbit (13)

Product Group

IHCPlus (1)

Isotype

IgG (7)

Clonality

polyclonal pc (13)

Format

96-Well Strip Plate (2)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (10)

Epitope

aa66-115 (4)

aa1-50 (1)

aa350-400 (1)

Publications

No (20)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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RNGTT / HCAP Antibody LS-C482608

Antibody:

RNGTT / HCAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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IHC-plus™ RNGTT / HCAP Antibody LS-B8904

(4.0) Rating

Antibody:

RNGTT / HCAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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RNGTT / HCAP Antibody LS-C676413

Antibody:

RNGTT / HCAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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RNGTT / HCAP Antibody LS-C335668

Antibody:

RNGTT / HCAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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RNGTT / HCAP Antibody (aa350-400) LS-C289587

Antibody:

RNGTT / HCAP Rabbit anti-Human Polyclonal (aa350-400) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

100 µl/$456

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RNGTT / HCAP Antibody (aa1-50) LS-C289586

Antibody:

RNGTT / HCAP Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

100 µl/$456

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RNGTT / HCAP Antibody LS-C770308

Antibody:

RNGTT / HCAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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RNGTT / HCAP Antibody LS-C660568

Antibody:

RNGTT / HCAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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RNGTT / HCAP Antibody LS-C817140

Antibody:

RNGTT / HCAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$412

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RNGTT / HCAP Antibody (aa66-115) LS-C146391

Antibody:

RNGTT / HCAP Rabbit anti-Mouse Polyclonal (aa66-115) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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RNGTT / HCAP Antibody (aa66-115, HRP) LS-C451398

Antibody:

RNGTT / HCAP Rabbit anti-Mouse Polyclonal (aa66-115) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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RNGTT / HCAP Antibody (aa66-115, Biotin) LS-C451396

Antibody:

RNGTT / HCAP Rabbit anti-Mouse Polyclonal (aa66-115) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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RNGTT / HCAP Antibody (aa66-115, FITC) LS-C451397

Antibody:

RNGTT / HCAP Rabbit anti-Mouse Polyclonal (aa66-115) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Human RNGTT / HCAP Protein (Recombinant GST) (Full Length) - LS-G31301

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

94.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human RNGTT / HCAP Protein (Recombinant His) - LS-G3019

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

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Mouse RNGTT / HCAP (Custom) ELISA Kit - LS-F66147

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

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Human RNGTT / HCAP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67496

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.4 kDa

Price:

20 µg/$1,107

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Human RNGTT / HCAP (Custom) ELISA Kit - LS-F65805

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Price:

1 Plate/$783

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Human RNGTT / HCAP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79988

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.4 kDa

Price:

20 µg/$150

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RNGTT / HCAP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100134

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.4 kDa

Price:

100 µg/$494

Viewing 1-20 of 20 product results

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