RNF43

ring finger protein 43

RNF43 is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

RNF43 (3)

Publications

No (3)

Tag

His,C-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

Low Endotoxin Level

Low endotoxin level (1)

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RNF43 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112238

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.7 kDa

Price:

100 µg/$710

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Human RNF43 Protein (Recombinant His,C-terminus) (Met1-Tyr197) - LS-G137996

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.5 kDa

Price:

100 µg/$721

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Human RNF43 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86238

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.7 kDa

Price:

20 µg/$215

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