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RNF213

ring finger protein 213

RNF213 is a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants.

Gene Name: ring finger protein 213
Synonyms: RNF213, C17orf27, KIAA1618, KIAA1554, Mysterin, MYSTR, ALO17, Moyamoya disease 2, MYMY2, NET57, Ring finger protein 213
Target Sequences: NM_020954 NP_066005.2 Q63HN8

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
RNF213 (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
RNF213 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RNF213 Protein - Purified recombinant protein RNF213 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
118.3 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
118.3 kDa
20 µg/$150
RNF213 Protein - 12.5% SDS-PAGE of human KIAA1618 stained with Coomassie Blue
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Wheat Germ Extract
GST
144.8 kDa
2 µg/$439
RNF213 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
118.3 kDa
100 µg/$494
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).