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RNF114 / ZNF313

ring finger protein 114

E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.

Gene Name: ring finger protein 114
Family/Subfamily: Zinc Finger
Synonyms: RNF114, PSORS12, Ring finger protein 114, Zinc finger protein 313, ZNF228, ZNF313, Zinc finger protein 228
Target Sequences: NM_018683 NP_061153.1 Q9Y508

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).