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RND2 is a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1.
Gene Name: | Rho family GTPase 2 |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
Synonyms: | RND2, ARHN, GTP-binding protein Rho7, Rho family GTPase 2, RHO7, RhoN |
Target Sequences: | NM_005440 NP_005431.1 P52198 |
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