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RNASEH1

ribonuclease H1

RNASEH1 is an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which overlaps the first initiation start codon in human. An alternately spliced transcript variant has been found which encodes a shorter isoform. This gene has three pseudogenes; two of them are at different locations of chromosome 17 and one of them is on chromosome 1q32.2.

Gene Name: ribonuclease H1
Synonyms: RNASEH1, H1RNA, RNase H1, Ribonuclease H type II, Ribonuclease H1
Target Sequences: NM_002936 NP_002927.2 O60930

☰ Filters
Antibodies (13)
Proteins (7)
Over-Expression Lysate (2)
Primary (13)
Recombinant (5)
RNASEH1 (20)
Human (13)
Mouse (6)
Rat (6)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Hamster (3)
Horse (3)
Rabbit (3)
IHC (6)
IHC-P (5)
WB (10)
ELISA (6)
IF (1)
IP (2)
Peptide-ELISA (1)
rabbit (12)
mouse (1)
Product Group
IHCPlus (1)
IgG (12)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (12)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (7)
C-Terminus (4)
aa7-461 (1)
No (20)
6His, N-terminus (2)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (3)
RNASEH1 Antibody - Western blot analysis of extracts of various cell lines.
Select
RNASEH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RNASEH1 Antibody - 1:100 staining rat lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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RNASEH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RNASEH1 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNASEH1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
RNASEH1 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNASEH1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Gibbon, Chimpanzee, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
RNASEH1 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNASEH1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Gibbon, Chimpanzee, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
RNASEH1 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RNASEH1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Gibbon, Chimpanzee, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
RNASEH1 Antibody - Immunohistochemistry Dilution at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Select
RNASEH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
RNASEH1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
RNASEH1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
RNASEH1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
RNASEH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$341
Select
RNASEH1 Mouse anti-Human Monoclonal (aa7-461) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$586
RNASEH1 Antibody - Western blot analysis of extracts of various cell lines using RNASEH1 Polyclonal Antibody at dilution of 1:1000.
Select
RNASEH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
RNASEH1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His, N-terminus
37.6 kDa
20 µg/$364; 1 mg/$1,679; 100 µg/$500
RNASEH1 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
6His, N-terminus
34 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
RNASEH1 Protein - 12.5% SDS-PAGE of human RNASEH1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
58.5 kDa
2 µg/$439
RNASEH1 Protein - Purified recombinant protein RNASEH1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
31.9 kDa
20 µg/$1,107
RNASEH1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
293T Cells
Myc-DDK (Flag)
31.9 kDa
20 µg/$150
RNASEH1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
31.9 kDa
100 µg/$494
Viewing 1-20 of 20 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).