RMA1 / RNF5

ring finger protein 5, E3 ubiquitin protein ligase

Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation; the ubiquitination occurrs in mitochondria after viral transfection and regulates antiviral responses.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

RMA1 / RNF5 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human RMA1 / RNF5 Protein (Recombinant GST) (Full Length) - LS-G30185

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

45.43 kDa

Price:

10 µg/$479; 25 µg/$670

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Human RMA1 / RNF5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83355

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

19.7 kDa

Price:

20 µg/$150

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RMA1 / RNF5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100941

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

19.7 kDa

Price:

100 µg/$494

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