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RITA1 / C12orf52

RBPJ interacting and tubulin associated 1

Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

Gene Name: RBPJ interacting and tubulin associated 1
Synonyms: RITA1, C12orf52, RITA
Target Sequences: NM_032848 CAC32398.1 Q96K30

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
RITA1 / C12orf52 (3)
No (3)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
RITA1 / C12orf52 Protein - Purified recombinant protein RITA1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
28.4 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
28.4 kDa
20 µg/$150
RITA1 / C12orf52 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
28.4 kDa
100 µg/$494
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).