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RIN1

Ras and Rab interactor 1

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Gene Name: Ras and Rab interactor 1
Synonyms: RIN1, Ras and Rab interactor 1, Ras inhibitor JC99, Ras inhibitor 1, Ras inhibitor RIN1
Target Sequences: NM_004292 NP_004283.2 Q13671

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Proteins (2)
Recombinant (2)
RIN1 (2)
No (2)
GST (1)
GST, N-terminus (1)
Human (2)
Wheat Germ Extract (2)
Purified (1)
RIN1 Protein - 12.5% SDS-PAGE of human RIN1 stained with Coomassie Blue
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Wheat Germ Extract
GST
110.5 kDa
2 µg/$439
RIN1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).