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RHOD
ras homolog family member D
Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution.
| Gene Name: | ras homolog family member D |
| Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
| Synonyms: | RHOD, ARHD, RHOHP1, Ras homolog D, Ras homolog family member D, RHOM, Rho-related protein HP1, Rho-related GTP-binding protein RhoD |
| Target Sequences: | NM_014578 NP_055393.1 O00212 |
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