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RHOBTB3

Rho-related BTB domain containing 3

Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9.

Gene Name: Rho-related BTB domain containing 3
Synonyms: RHOBTB3, KIAA0878
Target Sequences: NM_014899 NP_055714.3 O94955

Publications (1)

1
SPOP suppresses prostate cancer through regulation of CYCLIN E1 stability. Ju LG, Zhu Y, Long QY, Li XJ, Lin X, Tang SB, Yin L, Xiao Y, Wang XH, Li L, Zhang L, Wu M. Cell death and differentiation. 2019 June;26:1156-1168. [Full Text Article] [PubMed:30237511] [PMC:PMC6748103] Related Antibodies: LS-C385850.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).