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RHOB

ras homolog family member B

Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

Gene Name: ras homolog family member B
Family/Subfamily: Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806
Synonyms: RHOB, Aplysia RAS-related homolog 6, ARH6, H6, MST081, Oncogene RHO H6, RHOH6, Ras homolog family member B, ARHB, Transforming protein rhob, MSTP081, Rho cDNA clone 6
Target Sequences: NM_004040 NP_004031.1 P62745

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Products
ELISA Kits (5)
Sandwich (5)
RHOB (5)
Human (1)
Chicken (1)
Monkey (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (1)
96-Well Strip Plate (4)
No (5)
Plasma (1)
Serum (1)
RHOB ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
3.125 - 200 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
RHOB ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
RHOB ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
RHOB ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
2.5 - 160 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
RHOB ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).