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Lynnwood, WA 98036
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RHCE / RH
Rh blood group, CcEe antigens
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms.
| Gene Name: | Rh blood group, CcEe antigens |
| Synonyms: | RHCE, Blood group Rh(CE) polypeptide, Blood group RhCcEe antigen, CD240CE, CD240CE antigen, RH, Rh polypeptide I, Rhesus blood group CE protein, Rhesus blood group E antigen, RhIVb(J), Rh blood group Rhce antigen, Rh blood group, CcEe antigens, Rh polypeptide 1, Rh30a, Rh4, Rhesus C/E antigens, Rh blood group C antigen, RhVIII, Rh blood group antigen Evans, RHC, RHE, RHIXB, RHPI, RhVI |
| Target Sequences: | NM_020485 NP_065231.3 |
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