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RHBDD1

rhomboid domain containing 1

Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion; inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis; modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis; inhibits apoptotic activity in spermatogonia.

Gene Name: rhomboid domain containing 1
Synonyms: RHBDD1, Rhomboid domain containing 1, RRP4
Target Sequences: NM_032276 NP_115652.2 Q8TEB9

☰ Filters
Antibodies (9)
Proteins (5)
Over-Expression Lysate (4)
Primary (9)
Recombinant (1)
RHBDD1 (14)
Human (9)
Mouse (4)
Rat (1)
Orangutan (3)
IHC (4)
IHC-P (4)
WB (9)
ELISA (2)
rabbit (9)
Product Group
IHCPlus (1)
IgG (5)
polyclonal pc (9)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (6)
C-Terminus (4)
No (14)
Myc-DDK (Flag) (5)
Human (3)
293T Cells (2)
HEK 293 Cells (3)
RHBDD1 Antibody - Western blot of RHBDD1 in K562 cell lysate with RHBDD1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
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RHBDD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
0.1 mg/$460
RHBDD1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RHBDD1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
RHBDD1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RHBDD1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human, Orangutan
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
RHBDD1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RHBDD1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human, Orangutan
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
RHBDD1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RHBDD1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human, Orangutan
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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RHBDD1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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RHBDD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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RHBDD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
RHBDD1 Antibody - Western blot analysis of extracts of various cell lines, using RHBDD1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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RHBDD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RHBDD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
36.3 kDa
20 µg/$150
RHBDD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
35.6 kDa
20 µg/$150
RHBDD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
35.6 kDa
100 µg/$494
RHBDD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.3 kDa
100 µg/$494
RHBDD1 Protein - Purified recombinant protein RHBDD1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
35.6 kDa
20 µg/$1,107
Viewing 1-14 of 14 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).