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RGS3
regulator of G-protein signaling 3
RGS3 is a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear.
| Gene Name: | regulator of G-protein signaling 3 |
| Family/Subfamily: | Regulator of G-protein signalling , not assigned-Regulator of G-protein signalling |
| Synonyms: | RGS3, C2PA, RGP3, PDZ-RGS3 |
| Target Sequences: | NM_021106 NP_066929.1 P49796 |
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