RGS14

regulator of G-protein signaling 14

Acts as a regulator of G protein signaling (RGS). Modulates G protein alpha subunits nucleotide exchange and hydrolysis activities by functioning either as a GTPase-activating protein (GAP), thereby driving G protein alpha subunits into their inactive GDP-bound form, or as a GDP-dissociation inhibitor (GDI). Confers GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not G(o) alpha subunit GNAO1 and G(i) alpha subunit GNAI2. Confers GAP activity on G(o) alpha subunit GNAI0 and G(i) alpha subunits GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation; a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division. Probably required for the nerve growth factor (NGF)-mediated neurite outgrowth. May be involved in visual memory processing capacity and hippocampal-based learning and memory.

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Products

Antibodies (29)

Type

Primary (29)

Target

RGS14 (29)

Reactivity

Human (28)

Mouse (12)

Rat (7)

Bat (4)

Bovine (1)

Chimpanzee (3)

Gibbon (3)

Guinea pig (1)

Monkey (5)

Orangutan (3)

Pig (1)

Rabbit (1)

Sheep (1)

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Application

IHC (4)

IHC-P (3)

WB (26)

ELISA (13)

IF (1)

IP (3)

Peptide-ELISA (3)

Host

rabbit (26)

mouse (1)

goat (1)

rabbit-new zealand white (1)

Isotype

IgG (18)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (28)

Clone

2F8 (1)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (21)

Epitope

aa223-251 (7)

aa201-250 (4)

100-180 aa, Internal (1)

aa1-50 (1)

aa110-159 (1)

aa359-372 (1)

aa380-430 (1)

aa402-414 (1)

aa504-566 (1)

aa516-566 (1)

Publications

No (29)

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RGS14 Antibody (aa110-159) LS-C200596

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa110-159) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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RGS14 Antibody (clone 2F8) LS-C134027

Antibody:

RGS14 Mouse anti-Human Monoclonal (2F8) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µg/$423

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RGS14 Antibody LS-C676389

Antibody:

RGS14 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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RGS14 Antibody LS-C805326

Antibody:

RGS14 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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RGS14 Antibody (aa504-566) LS-C185806

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa504-566) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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RGS14 Antibody LS-C660531

Antibody:

RGS14 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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RGS14 Antibody (aa380-430) LS-C829723

Antibody:

RGS14 Rabbit-New Zealand White anti-Human Polyclonal (aa380-430) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

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RGS14 Antibody LS-C742710

Antibody:

RGS14 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

RGS14 Antibody (aa223-251) LS-C324645

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa223-251) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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RGS14 Antibody (aa223-251, Biotin) LS-C268173

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa223-251) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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RGS14 Antibody (aa223-251, FITC) LS-C268175

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa223-251) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

RGS14 Antibody (aa223-251, APC) LS-C268172

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa223-251) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

RGS14 Antibody (aa223-251, PE) LS-C268176

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa223-251) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

RGS14 Antibody (aa223-251, Azide-free, HRP) LS-C268174

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa223-251) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

RGS14 Antibody (100-180 aa, Internal) LS-C385842

Antibody:

RGS14 Rabbit anti-Human Polyclonal (100-180 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

RGS14 Antibody LS-C676390

Antibody:

RGS14 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

RGS14 Antibody LS-C824512

Antibody:

RGS14 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

RGS14 Antibody (aa516-566) LS-C290449

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa516-566) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

RGS14 Antibody (aa402-414) LS-C55387

Antibody:

RGS14 Goat anti-Human Polyclonal (aa402-414) Antibody

Reactivity:

Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

RGS14 Antibody (aa201-250) LS-C169513

Antibody:

RGS14 Rabbit anti-Mouse Polyclonal (aa201-250) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

RGS14 Antibody (aa223-251) LS-C162573

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa223-251) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

RGS14 Antibody (aa359-372) LS-C313270

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa359-372) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat, Pig, Bat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

RGS14 Antibody LS-C668151

Antibody:

RGS14 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

RGS14 Antibody LS-C760996

Antibody:

RGS14 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

Select

RGS14 Antibody (aa1-50) LS-C290445

Antibody:

RGS14 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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