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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RGS14

regulator of G-protein signaling 14

Acts as a regulator of G protein signaling (RGS). Modulates G protein alpha subunits nucleotide exchange and hydrolysis activities by functioning either as a GTPase-activating protein (GAP), thereby driving G protein alpha subunits into their inactive GDP-bound form, or as a GDP-dissociation inhibitor (GDI). Confers GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not G(o) alpha subunit GNAO1 and G(i) alpha subunit GNAI2. Confers GAP activity on G(o) alpha subunit GNAI0 and G(i) alpha subunits GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation; a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division. Probably required for the nerve growth factor (NGF)-mediated neurite outgrowth. May be involved in visual memory processing capacity and hippocampal-based learning and memory.

Gene Name: regulator of G-protein signaling 14
Family/Subfamily: Regulator of G-protein signalling , not assigned-Regulator of G-protein signalling
Synonyms: RGS14
Target Sequences: NM_006480 NP_006471.2 O43566

Filtered By: None
Target
RGS14 (26)
Reactivity
Human (26)
Mouse (10)
Rat (5)
Bat (5)
Bovine (2)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (2)
Horse (1)
Monkey (7)
Orangutan (3)
Pig (1)
Rabbit (2)
Sheep (1)
Application
IHC (3)
IHC-P (3)
WB (23)
ELISA (13)
IP (3)
Peptide-ELISA (2)
Host
rabbit (24)
mouse (1)
goat (1)
Isotype
IgG (17)
IgG1,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (25)
Clone
2F8 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (17)
Epitope
aa223-251 (8)
aa201-250 (4)
100-180 aa, Internal (1)
aa1-50 (1)
aa110-159 (1)
aa359-372 (1)
aa402-414 (1)
aa504-566 (1)
aa516-566 (1)
Publications
No (26)
Showing 1-25 of 26 results

RGS14 Antibody (clone 2F8) LS-C134027
Mouse Monoclonal [clone 2F8] (IgG1,k) to Human RGS14
Human
ELISA IHC IHC-P
Unconjugated
100µg  $355.00
Immunoperoxidase of monoclonal antibody to RGS14 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]
Detection limit for recombinant GST tagged RGS14 is 0.1 ng/ml as a capture antibody.
Immunoperoxidase of monoclonal antibody to RGS14 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]
Detection limit for recombinant GST tagged RGS14 is 0.1 ng/ml as a capture antibody.

RGS14 Antibody LS-C676389
Rabbit Polyclonal (IgG) to Human RGS14
Human
ELISA IHC IHC-P
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100

RGS14 Antibody (aa504-566) LS-C185806
Rabbit Polyclonal (IgG) to Human RGS14
Human
IHC IHC-P WB
Unconjugated
100µl 0.93mg/ml  $335.00
IHC of paraffin-embedded GASTRIC CA using RGS14 antibody at 1:100 dilution.
RGS14 antibody [C3], C-term detects RGS14 protein by Western blot analysis. A. 30 ug Jurkat whole lysate/extract. 7.5 % SDS-PAGE. RGS14 antibody [C3], C-term dilution:1:500
IHC of paraffin-embedded GASTRIC CA using RGS14 antibody at 1:100 dilution.
RGS14 antibody [C3], C-term detects RGS14 protein by Western blot analysis. A. 30 ug Jurkat whole lysate/extract. 7.5 % SDS-PAGE. RGS14 antibody [C3], C-term dilution:1:500

RGS14 Antibody LS-C660531
Rabbit Polyclonal (IgG) to Human RGS14
Human
ELISA IP WB
Unconjugated
100µg  $435.00

RGS14 Antibody (aa223-251) LS-C324645
Rabbit Polyclonal (IgG) to Human RGS14
Human
ELISA WB
Unconjugated
200µl  $530.00

RGS14 Antibody (aa223-251, Biotin) LS-C268173
Rabbit Polyclonal (IgG) to Human RGS14
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

RGS14 Antibody (aa223-251, FITC) LS-C268175
Rabbit Polyclonal (IgG) to Human RGS14
Human
ELISA WB
FITC Conjugated
200µl  $680.00

RGS14 Antibody (aa223-251, APC) LS-C268172
Rabbit Polyclonal (IgG) to Human RGS14
Human
ELISA WB
APC Conjugated
200µl  $680.00

RGS14 Antibody (aa223-251, AP) LS-C268170
Rabbit Polyclonal (IgG) to Human RGS14
Human
ELISA WB
AP Conjugated
200µl  $680.00

RGS14 Antibody (aa223-251, PE) LS-C268176
Rabbit Polyclonal (IgG) to Human RGS14
Human
ELISA WB
PE Conjugated
200µl  $680.00

RGS14 Antibody (aa223-251, Azide-free, HRP) LS-C268174
Rabbit Polyclonal (IgG) to Human RGS14
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

RGS14 Antibody LS-C742710
Rabbit Polyclonal (IgG) to Human RGS14
Mouse, Rat, Human
ELISA WB
Unconjugated
50µg 1mg/ml  $265.00; 100µg 1mg/ml  $325.00

RGS14 Antibody (100-180 aa, Internal) LS-C385842
Rabbit Polyclonal (IgG) to Human RGS14
Mouse, Rat, Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of RGS14 antibody
Western blot of RGS14 antibody

RGS14 Antibody LS-C676390
Rabbit Polyclonal (IgG) to Human RGS14
Human
ELISA WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Western blot All Lanes: RGS14 antibody at 3.88ug/ml Lane 1: 293T whole cell lysate Lane 2: Hela whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: SH-SY5Y whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 62,22,45,37 kDa Observed band size: 61 kDa
Western blot All Lanes: RGS14 antibody at 3.88ug/ml Lane 1: 293T whole cell lysate Lane 2: Hela whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: SH-SY5Y whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 62,22,45,37 kDa Observed band size: 61 kDa

RGS14 Antibody (aa516-566) LS-C290449
Rabbit Polyclonal (IgG) to Human RGS14
Human, Monkey
IP WB
Unconjugated
100µl 1mg/ml  $395.00

RGS14 Antibody (aa110-159) LS-C200596
Rabbit Polyclonal (IgG) to Human RGS14
Mouse, Rat, Human
Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of the lysates from HUVECcells using RGS14 antibody.
Western blot analysis of the lysates from HUVECcells using RGS14 antibody.

RGS14 Antibody (aa402-414) LS-C55387
Goat Polyclonal to Human RGS14
Human, Monkey
Peptide-ELISA WB
Unconjugated
100µg  $405.00
Antibody staining (0.5 ug/ml) of Jurkat lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
Antibody staining (0.5 ug/ml) of Jurkat lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

RGS14 Antibody (aa201-250) LS-C169513
Rabbit Polyclonal to Mouse RGS14
Mouse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
 This image was taken for the unconjugated form of this product. Other forms have not been tested.

RGS14 Antibody (aa201-250, Biotin) LS-C430485
Rabbit Polyclonal to Mouse RGS14
Mouse, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
 This image was taken for the unconjugated form of this product. Other forms have not been tested.

RGS14 Antibody (aa201-250, FITC) LS-C430486
Rabbit Polyclonal to Mouse RGS14
Mouse, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan
WB
FITC Conjugated
100µl 1mg/ml  $385.00
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
 This image was taken for the unconjugated form of this product. Other forms have not been tested.

RGS14 Antibody (aa359-372) LS-C313270
Rabbit Polyclonal to Human RGS14
Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat, Pig, Bat, Human, Monkey
WB
Unconjugated
100µg 200µl 0.5mg/ml  $305.00
WB of RGS14 antibody. Lane 1: Rat Thymus Tissue Lysate. Lane 2: Rat Spleen Tissue Lysate. Lane 3: RAJI Cell Lysate. Lane 4: CEM Cell Lysate. Lane 5: JURKAT Cell Lysate.
WB of RGS14 antibody. Lane 1: Rat Thymus Tissue Lysate. Lane 2: Rat Spleen Tissue Lysate. Lane 3: RAJI Cell Lysate. Lane 4: CEM Cell Lysate. Lane 5: JURKAT Cell Lysate.

RGS14 Antibody (aa223-251) LS-C162573
Rabbit Polyclonal to Human RGS14
Human
WB
Unconjugated
400µl  $305.00
RGS14 Antibody western blot of U937 cell line lysates (35 ug/lane). The RGS14 antibody detected the RGS14 protein (arrow).
RGS14 Antibody western blot of U937 cell line lysates (35 ug/lane). The RGS14 antibody detected the RGS14 protein (arrow).

RGS14 Antibody LS-C411455
Rabbit Polyclonal (IgG) to Human RGS14
Mouse, Human
WB
Unconjugated
50µl  $255.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cells.
Western blot analysis of extracts of various cells.

RGS14 Antibody LS-C668151
Rabbit Polyclonal to Human RGS14
Human
WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Western blot Image
Western blot Image

RGS14 Antibody (aa1-50) LS-C290445
Rabbit Polyclonal (IgG) to Human RGS14
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Human
IP
Unconjugated
100µl 1mg/ml  $395.00
Showing 1-25 of 26 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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