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RGS11
regulator of G-protein signaling 11
RGS11 belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
| Gene Name: | regulator of G-protein signaling 11 |
| Family/Subfamily: | Regulator of G-protein signalling , not assigned-Regulator of G-protein signalling |
| Synonyms: | RGS11, RS11 |
| Target Sequences: | NM_003834 NP_003825.1 O94810 |
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