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RGS10

regulator of G-protein signaling 10

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: regulator of G-protein signaling 10
Family/Subfamily: Regulator of G-protein signalling , not assigned-Regulator of G-protein signalling
Synonyms: RGS10
Target Sequences: NM_002925 NP_002916.1 O43665

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Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
RGS10 (10)
No (10)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (6)
Human (7)
Mouse (1)
293T Cells (2)
E. coli (3)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (4)
RGS10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21 kDa
100 µg/$494
RGS10 Protein - Recombinant Regulator Of G Protein Signaling 10 (RGS10) by SDS-PAGE
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E. coli
None
23.1kDa
10 µg/$268; 50 µg/$362; 200 µg/$722; 100 µg/$577; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
RGS10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
19.4 kDa
100 µg/$494
RGS10 Protein - 12.5% SDS-PAGE of human RGS10 stained with Coomassie Blue
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Wheat Germ Extract
GST
45.65 kDa
10 µg/$479; 25 µg/$670
RGS10 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RGS10 Protein - Purified recombinant protein RGS10 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
19.4 kDa
20 µg/$1,107
RGS10 Protein - Purified recombinant protein RGS10 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
21 kDa
20 µg/$1,107
RGS10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
21 kDa
20 µg/$150
RGS10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
19.4 kDa
20 µg/$150
RGS10 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).