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RGMB

repulsive guidance molecule family member b

Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.

Gene Name: repulsive guidance molecule family member b
Synonyms: RGMB, DRAGON, Repulsive guidance molecule B, RGM domain family member B, RGM domain family, member B
Target Sequences: Q6NW40 Q6NW40

Publications (2)

1
RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival. Rostislav Novak, Yamen Abu Ahmad, Michael Timaner, Eliya Bitman-Lotan, Avital Oknin-Vaisman, Roi Horwitz, Oliver Hartmann, Michaela Reissland, Viktoria Buck, Mathias Rosenfeldt, David Nikomarov, Markus Elmar Diefenbacher, Yuval Shaked, Amir Orian. Cell death & disease. 2022 September;13:820. [Full Text Article] [PubMed:36153321] [PMC:PMC9509360] Related Antibodies: LS-C185861.
2
Human sensory neurons modulate melanocytes through secretion of RGMB. Siu Yu A Chow, Kazuki Nakayama, Tatsuya Osaki, Maki Sugiyama, Maiko Yamada, Hirotaka Takeuchi, Yoshiho Ikeuchi. Cell reports. 2022 September;40:111366. [Full Text Article] [PubMed:36130522]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).