RGCC

regulator of cell cycle

RGCC is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

RGCC (5)

Publications

No (5)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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RGCC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114167

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.4 kDa

Price:

100 µg/$494

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Human RGCC Protein (Recombinant His) (aa1-137) - LS-G26203

Source:

E. coli

Tag:

His

Molecular Weight:

18.3 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human RGCC Protein (Recombinant GST) (Full Length) - LS-G33371

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

39.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human RGCC Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69182

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.4 kDa

Price:

20 µg/$1,107

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Human RGCC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84007

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.4 kDa

Price:

20 µg/$150

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