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RFXANK

regulatory factor X-associated ankyrin-containing protein

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: regulatory factor X-associated ankyrin-containing protein
Synonyms: RFXANK, ANKRA1, BLS, DNA-binding protein RFXANK, F14150_1, RFXB, RFX-B, Regulatory factor X subunit B, RFX-Bdelta4
Target Sequences: NM_003721 NP_003712.1 O14593

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Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
RFXANK (8)
No (8)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (5)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (2)
RFXANK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
25.4 kDa
100 µg/$494
RFXANK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
27.9 kDa
20 µg/$150
RFXANK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.4 kDa
20 µg/$150
RFXANK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
27.9 kDa
100 µg/$494
RFXANK Protein
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E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
RFXANK Protein - 12.5% SDS-PAGE of human RFXANK stained with Coomassie Blue
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Wheat Germ Extract
GST
52 kDa
10 µg/$479; 25 µg/$670
RFXANK Protein - Purified recombinant protein RFXANK was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
27.9 kDa
20 µg/$1,107
RFXANK Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).