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RERE is a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | arginine-glutamic acid dipeptide (RE) repeats |
Synonyms: | RERE, ARG, Atrophin-1 like protein, ARP, ATN1L, Atrophin-1 related protein, Atrophin-1-like protein, DNB1, KIAA0458, Atrophin 2, Atrophin-1-related protein |
Target Sequences: | NM_012102 NP_036234.3 Q9P2R6 |
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