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RENBP

renin binding protein

Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.

Gene Name:	renin binding protein
Synonyms:	RENBP, AGE, RNBP, Renin-binding protein, GlcNAc 2-epimerase, N-acylglucosamine 2-epimerase, RBP, Renin binding protein
Target Sequences:	NM_002910 NP_002901.2 P51606

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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