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Renal Dipeptidase / DPEP1

dipeptidase 1 (renal)

Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.

Gene Name: dipeptidase 1 (renal)
Family/Subfamily: Exopeptidase , Metallopeptidase M19
Synonyms: DPEP1, Dipeptidase 1 (renal), Dehydropeptidase-I, Dipeptidase 1, HRDP, Microsomal dipeptidase, Renal dipeptidase, RDP
Target Sequences: NM_004413 NP_004404.1 P16444

Publications (1)

1
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets. Qin Zhang , Dennis K Jeppesen , James N Higginbotham , Ramona Graves-Deal, Vincent Q Trinh, Marisol A Ramirez, Yoojin Sohn, Abigail C Neininger, Nilay Taneja, Eliot T McKinley, Hiroaki Niitsu, Zheng Cao, Rachel Evans, Sarah E Glass, Kevin C Ray, William H Fissell, Salisha Hill, Kristie Lindsey Rose, Won Jae Huh, Mary Kay Washington, Gregory Daniel Ayers, Dylan T Burnette, Shivani Sharma, Leonard H Rome, Jeffrey L Franklin, Youngmin A Lee, Qi Liu, Robert J Coffey. Nature cell biology. 2021 December;23:1240-1254. [Full Text Article] [PubMed:34887515] [PMC:PMC8656144] Related Antibodies: LS-A109972.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).