REN / Renin 1

Renin

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.

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Products

Proteins (18)

Type

Over-Expression Lysate (2)

Recombinant (16)

Target

REN / Renin 1 (18)

Application

Bind (1)

ELISA (1)

Func (1)

SDS-PAGE (1)

Publications

No (18)

Tag

10His, C-terminus (1)

GST (1)

His (5)

His, C-Terminal (1)

His, N-Terminal (2)

His,C-terminus (4)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (10)

Mouse (5)

Rat (2)

Source

293T Cells (1)

E. coli (7)

HEK 293 Cells (4)

Human (2)

Human Cells (1)

Mammalian Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (8)

Biologically Active

Biologically active (1)

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Human REN / Renin 1 Protein (Recombinant His,C-terminus) (Met1-Arg406) - LS-G48387

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

Bind ELISA Func SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The secreted recombinant human Renin is a monomeric protein after cleavage of the signal peptide. The pro form consists of 394 amino acids and predictes a molecular mass of 43.7 kDa. In SDS-PAGE under reducing conditions, it migrates with the apparent molecular mass of 50 kDa due to glycosylation.

Price:

50 µg/$441; 1 mg/$2,333

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Human REN / Renin 1 Protein (Recombinant His) - LS-G2403

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human REN / Renin 1 Protein (Recombinant 10His, C-terminus) (Leu24-Arg406) - LS-G55703

Source:

Human

Tag:

10His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44kD

Price:

10 µg/$277; 50 µg/$395; 500 µg/$1,377; 1 mg/$1,765

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Rat REN / Renin 1 Protein (Recombinant His, N-Terminal) (aa275-389) - LS-G13055

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

14.2 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Rat REN / Renin 1 Protein (Recombinant His, N-Terminal) (aa144-237) - LS-G13063

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

11.7 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Mouse REN / Renin 1 Protein (Recombinant His) (aa265-386) - LS-G13054

Source:

E. coli

Tag:

His

Molecular Weight:

14.7 kDa

Price:

10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136

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REN / Renin 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123129

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.06 kDa

Price:

100 µg/$494

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Human REN / Renin 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87283

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.06 kDa

Price:

20 µg/$150

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Mouse REN / Renin 1 Protein (Recombinant His,C-terminus) (Met1-Arg402) - LS-G140782

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

43.2 kDa

Price:

50 µg/$721

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Human REN / Renin 1 Protein (Recombinant GST) (Full Length) - LS-G30148

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

67.87 kDa

Price:

10 µg/$479; 25 µg/$670

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Human REN / Renin 1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70510

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.3 kDa

Price:

20 µg/$1,107

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Human REN / Renin 1 Protein (Recombinant His) (aa1-406) - LS-G141049

Source:

E. coli

Sequence Length:

405 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

44.66 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

Select

Human REN / Renin 1 Protein (Recombinant His,C-terminus) (Leu24-Arg406) - LS-G139226

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44 kDa

Price:

10 µg/$277; 50 µg/$389

Select

Mouse REN / Renin 1 Protein (Recombinant His,C-terminus) (Leu22-Arg402) - LS-G139317

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

43.5 kDa

Price:

10 µg/$277; 50 µg/$389

Select

Mouse REN / Renin 1 Protein (Recombinant His, C-Terminal) (Leu22-Arg402) - LS-G55704

Source:

Human

Tag:

His, C-Terminal

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

43.5kD

Price:

10 µg/$277; 50 µg/$395; 500 µg/$1,377; 1 mg/$1,765

Select

Human REN / Renin 1 Protein (Recombinant His) (Met1-Arg406) - LS-G98649

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

43.7 kDa

Price:

50 µg/$721

Select

Mouse REN / Renin 1 Protein (Recombinant His) (aa110-221) - LS-G13052

Source:

E. coli

Tag:

His

Molecular Weight:

13.4 kDa

Price:

10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136

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Human REN / Renin 1 Protein (Recombinant His-T7) (aa67-179) - LS-G13053

Source:

E. coli

Tag:

His-T7

Molecular Weight:

16.1 kDa

Price:

10 µg/$272; 50 µg/$387; 100 µg/$620; 200 µg/$772; 1 mg/$1,834; 500 µg/$1,393; 5 mg/$2,794; 2 mg/$2,016

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