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REN / Renin 1

Renin

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.

Gene Name: Renin
Family/Subfamily: Protease , Aspartic A1
Synonyms: REN, Angiotensin-forming enzyme, Angiotensinogenase, HNFJ2, RENAA, Renin precursor, renal, Renin
Target Sequences: NM_000537 NP_000528.1 P00797

Publications (3)

1
Heart Failure With Reduced Ejection Fraction Is Characterized by Systemic NEP Downregulation. Imre J Pavo, Noemi Pavo, Nina Kastner, Denise Traxler, Dominika Lukovic, Katrin Zlabinger, Andreas Spannbauer, Martin Riesenhuber, David Lorant, Philipp E Bartko, Georg Goliasch, Martin Hülsmann, Johannes Winkler, Mariann Gyöngyösi. JACC. Basic to translational science. 2020 July;5:715-726. [Full Text Article] [PubMed:32760858] [PMC:PMC7393434]
2
Full Issue PDF. No authors listed. JACC. Basic to translational science. 2020 July;5:I-CX. [Full Text Article] [PubMed:32835137] [PMC:PMC7384789]
3
Comparison of the expression of neurotransmitter and muscular genesis markers in the postnatal male mouse masseter and trigeminal ganglion during development. Hiroaki Kamata, Hiroyuki Karibe, Iwao Sato. Journal of neuroscience research. 2018 June;96:1043-1055. [Full Text Article] [PubMed:29265492]

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ELISA Kits (37)
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REN / Renin 1 (37)
Human (11)
Mouse (10)
Rat (5)
Chicken (1)
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Guinea pig (1)
Monkey (1)
Pig (2)
Rabbit (3)
12 x 8-Well Microstrips (3)
96-Well Microplate (9)
96-Well Strip Plate (25)
No (35)
Yes (2)
Cell Culture Supernatants (8)
Cell Lysates (3)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (33)
Serum (34)
Tissue Homogenates (10)
Urine (2)
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$795
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
12.21 - 50000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$840
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Microplate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Urine
1 Plate/$795
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Microplate
Pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,081
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
REN / Renin 1 ELISA Kit
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Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
REN / Renin 1 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
REN / Renin 1 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Rat
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
5 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
REN / Renin 1 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Microplate
Rabbit
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Urine
1 Plate/$717
REN / Renin 1 ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Human
5.49 - 4000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$968
REN / Renin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).