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REG3G

regenerating islet-derived 3 gamma

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.

Gene Name: regenerating islet-derived 3 gamma
Synonyms: REG3G, LPPM429, PAP1B, REG-3-gamma, Regenerating gene III, REG-III, UNQ429, PAP IB, PAP-1B, PAPIB, Reg III-gamma, Regenerating islet-derived protein 3-gamma
Target Sequences: NM_001008387 NP_001008388.1 Q6UW15

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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).