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REG3A

regenerating islet-derived 3 alpha

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.

Gene Name:	regenerating islet-derived 3 alpha
Synonyms:	REG3A, INGAP, HIP, PAP homologous protein, PAP1, REG-III, REG3, PAP-H, Reg III-alpha, REG-3-alpha, Human proislet peptide, PBCGF
Target Sequences:	NM_002580 NP_002571.1 Q06141

Publications (1)

Inflammation and nerve injury induce expression of pancreatitis-associated protein-II in primary sensory neurons. He SQ, Yao JR, Zhang FX, Wang Q, Bao L, Zhang X. Molecular pain. 2010 6:23. (IHC-Fr; Rat) [PubMed:20420691] [PMC:PMC2873504] Related Antibodies: LS-C38777.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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