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RCAN2 / RCN2
regulator of calcineurin 2
RCAN2 / RCN2 is a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
| Gene Name: | regulator of calcineurin 2 |
| Synonyms: | RCAN2, Calcipressin-2, CSP2, DSCR1L1, HRCN2, ZAKI-4, ZAKI4, MCIP2, Regulator of calcineurin 2 |
| Target Sequences: | NM_005822 NP_005813.2 Q14206 |
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