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RCAN1 / DSCR1

regulator of calcineurin 1

RCAN1 / DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.

Gene Name: regulator of calcineurin 1
Synonyms: RCAN1, ADAPT78, DSCR1, MCIP1, Regulator of calcineurin 1, Calcipressin-1, CSP1, Near DSCR proline-rich protein
Target Sequences: NM_004414 NP_004405.3 P53805

☰ Filters
Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
RCAN1 / DSCR1 (7)
No (7)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (1)
RCAN1 / DSCR1 Protein - 12.5% SDS-PAGE of human DSCR1 stained with Coomassie Blue
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Wheat Germ Extract
GST
47.41 kDa
10 µg/$479; 25 µg/$670
RCAN1 / DSCR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
22.6 kDa
20 µg/$150
RCAN1 / DSCR1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RCAN1 / DSCR1 Protein - Purified recombinant protein RCAN1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
27.9 kDa
20 µg/$1,107
RCAN1 / DSCR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
22.6 kDa
100 µg/$494
RCAN1 / DSCR1 Protein
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E. coli
None
100 µg/$411; 500 µg/$985; 20 µg/$276
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E. coli
251 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
27.72 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Viewing 1-7 of 7 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).