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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RCAN1 / DSCR1

regulator of calcineurin 1

RCAN1 / DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.

Gene Name: regulator of calcineurin 1
Synonyms: RCAN1, ADAPT78, DSCR1, MCIP1, Regulator of calcineurin 1, Calcipressin-1, CSP1, Near DSCR proline-rich protein
Target Sequences: NM_004414 NP_004405.3 P53805

Filtered by: None
Target
RCAN1 / DSCR1 (74)
Reactivity
Human (73)
Mouse (25)
Rat (19)
Bovine (11)
Chicken (1)
Chimpanzee (3)
Dog (9)
Gibbon (9)
Guinea pig (9)
Hamster (9)
Horse (9)
Monkey (9)
Orangutan (6)
Pig (8)
Rabbit (5)
Sheep (11)
Application
IHC (20)
IHC-P (10)
WB (70)
ELISA (31)
IF (4)
Peptide-ELISA (2)
Host
rabbit (69)
mouse (4)
goat (1)
Isotype
IgG (38)
IgG1 (2)
IgG1,k (1)
Clonality
monoclonal mc (3)
polyclonal pc (71)
Clone
1G7 (1)
OTI10C6 (2)
Format
AP Conjugated (3)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (10)
Carrier-free (1)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (8)
HRP Conjugated (8)
PE Conjugated (3)
Unconjugated (33)
Epitope
aa222-252 (8)
aa41-68 (8)
aa75-104 (8)
C-Terminus (5)
aa210-252 (5)
aa40-90 (5)
N-Terminus (4)
aa180-229 (4)
aa22-66 (4)
180-260 aa, C-terminal (1)
Internal (1)
aa145-157 (1)
aa190-239 (1)
aa207-252 (1)
Publications
No (74)
Showing 1-25 of 74 results

IHC-plus™ RCAN1 / DSCR1 Antibody (aa190-239) LS-B11434
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-RCAN1 / DSCR1 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Western blot analysis of the lysates from HT-29 cells using RCAN1 antibody.

RCAN1 / DSCR1 Antibody (aa180-229) LS-C101696
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $385.00
RCAN1 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

RCAN1 / DSCR1 Antibody (aa40-90) LS-C143371
Rabbit Polyclonal to Human RCAN1 / DSCR1
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $335.00
RCAN1 Antibody - IHC of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
RCAN1 Antibody - Western blot of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RCAN1 / DSCR1 Antibody (aa40-90, Biotin) LS-C143372
Rabbit Polyclonal to Human RCAN1 / DSCR1
Mouse, Human
IHC, IHC-P, WB
Biotin Conjugated
100µl  $365.00
RCAN1 Antibody - IHC of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
RCAN1 Antibody - Western blot of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RCAN1 / DSCR1 Antibody (aa40-90, DY488) LS-C143374
Rabbit Polyclonal to Human RCAN1 / DSCR1
Mouse, Human
IHC, IHC-P, WB
DY488 Conjugated
100µl  $365.00
RCAN1 Antibody - IHC of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
RCAN1 Antibody - Western blot of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RCAN1 / DSCR1 Antibody (aa40-90, DY550) LS-C143376
Rabbit Polyclonal to Human RCAN1 / DSCR1
Mouse, Human
IHC, IHC-P, WB
DY550 Conjugated
100µl  $365.00
RCAN1 Antibody - IHC of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
RCAN1 Antibody - Western blot of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RCAN1 / DSCR1 Antibody (aa40-90, DY650) LS-C143373
Rabbit Polyclonal to Human RCAN1 / DSCR1
Mouse, Human
IHC, IHC-P, WB
DY650 Conjugated
100µl  $365.00
RCAN1 Antibody - IHC of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
RCAN1 Antibody - Western blot of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RCAN1 / DSCR1 Antibody (aa145-157) LS-C154834
Goat Polyclonal to Human RCAN1 / DSCR1
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
RCAN1 antibody (1 ug/ml) staining of Mouse Brain and  KO Mouse Brain lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

RCAN1 / DSCR1 Antibody (Internal) LS-C94019
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
Mouse, Rat, Human
IHC, WB
Unconjugated
500µg  $325.00

RCAN1 / DSCR1 Antibody (aa210-252) LS-C143377
Rabbit Polyclonal to Human RCAN1 / DSCR1
Human
IHC, WB
Unconjugated
100µl 1mg/ml  $335.00
RCAN1 Antibody - IHC of RCAN1 in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
RCAN1 Antibody - Western blot of RCAN in human fetal brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ RCAN1 / DSCR1 Antibody (N-Terminus) LS-B11631
Rabbit Polyclonal to Human RCAN1 / DSCR1
Human
IHC, IHC-P, WB
Unconjugated
100µl  $485.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
RCAN1 antibody western blot of human placenta lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RCAN1 / DSCR1 Antibody (N-Terminus, HRP) LS-C464194
Rabbit Polyclonal to Human RCAN1 / DSCR1
Human, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
RCAN1 antibody western blot of human placenta lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RCAN1 / DSCR1 Antibody (N-Terminus, Biotin) LS-C464192
Rabbit Polyclonal to Human RCAN1 / DSCR1
Human, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
RCAN1 antibody western blot of human placenta lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RCAN1 / DSCR1 Antibody (N-Terminus, FITC) LS-C464193
Rabbit Polyclonal to Human RCAN1 / DSCR1
Human, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100µl 1mg/ml  $385.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
RCAN1 antibody western blot of human placenta lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

RCAN1 / DSCR1 Antibody LS-C333986
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
Mouse, Human
IF, IHC, WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Immunohistochemistry of paraffin-embedded human breast cancer using RCAN1 antibody at dilution of 1:200 (x400 lens).
Immunofluorescence analysis of U20S cell using RCAN1 antibody. Blue: DAPI for nuclear staining.

RCAN1 / DSCR1 Antibody LS-C412491
Rabbit Polyclonal to Human RCAN1 / DSCR1
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µl  $385.00

RCAN1 / DSCR1 Antibody LS-C406155
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
Mouse, Human
ELISA, IHC, WB
Unconjugated
20µl 0.1mg/ml  $205.00; 60µl 0.1mg/ml  $235.00; 120µl 0.1mg/ml  $295.00; 200µl 0.1mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human liver cancer using RCAN1 Polyclonal Antibody at dilution of 1:45.
Immunohistochemistry of paraffin-embedded Human brain using RCAN1 Polyclonal Antibody at dilution of 1:45.

RCAN1 / DSCR1 Antibody LS-C752465
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
Human
ELISA, IHC, WB
Unconjugated
100µg  $355.00

RCAN1 / DSCR1 Antibody (aa41-68) LS-C162511
Rabbit Polyclonal to Human RCAN1 / DSCR1
Human
IF, WB
Unconjugated
400µl  $325.00
Fluorescent confocal image of A431 cell stained with RCAN1 Antibody. A431 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with RCAN1 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). RCAN1 immunoreactivity is localized to Cytoplasm significantly.
Western blot of RCAN1 (arrow) using rabbit polyclonal RCAN1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RCAN1 gene.

RCAN1 / DSCR1 Antibody (clone 1G7) LS-C197083
Mouse Monoclonal [clone 1G7] (IgG1,k) to Human RCAN1 / DSCR1
Human
ELISA, WB
Unconjugated
200µl  $365.00
DSCR1 monoclonal antibody (M01A), clone 1G7. Western Blot analysis of DSCR1 expression in COLO 320 HSR.

RCAN1 / DSCR1 Antibody (aa41-68) LS-C324585
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
Human
ELISA, WB
Unconjugated
200µl  $590.00

RCAN1 / DSCR1 Antibody (aa222-252, Azide-free) LS-C326989
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
Human
ELISA, WB
Unconjugated, Azide-free
200µl  $590.00

RCAN1 / DSCR1 Antibody (aa75-104) LS-C35240
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
ELISA, WB
Unconjugated
200µl  $590.00

RCAN1 / DSCR1 Antibody LS-C742647
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
Mouse, Rat, Human
ELISA, WB
Unconjugated
50µg 1mg/ml  $265.00; 100µg 1mg/ml  $325.00

RCAN1 / DSCR1 Antibody LS-C804880
Rabbit Polyclonal (IgG) to Human RCAN1 / DSCR1
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Showing 1-25 of 74 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).