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RBSN / Rabenosyn 5

Rabenosyn, RAB effector

Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).

Gene Name: Rabenosyn, RAB effector
Synonyms: RBSN, 110 kDa protein, Rabenosyn-5, ZFYVE20
Target Sequences: NM_022340 NP_071735.2 Q9H1K0

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Proteins (2)
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RBSN / Rabenosyn 5 (2)
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HEK 293 Cells (1)
RBSN / Rabenosyn 5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
88.7 kDa
20 µg/$215
RBSN / Rabenosyn 5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
88.7 kDa
100 µg/$710
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).