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RBM22
RNA binding motif protein 22
Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
| Gene Name: | RNA binding motif protein 22 |
| Synonyms: | RBM22, FSAP47, Pre-mRNA-splicing factor RBM22, RNA-binding motif protein 22, ZC3H16, Cwc2, RNA binding motif protein 22 |
| Target Sequences: | NM_018047 NP_060517.1 Q9NW64 |
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